The Effect of Polyphenol Supplementation in People with Multiple Sclerosis: A Systematic Review of Clinical Trials
Lauren Brooks, Aqif Farhan bin Azmil Farid, Amudha Poobalan, Alexandra Johnstone, Phyo Kyaw Myint · 2026
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Description
Lauren Brooks leads a 2026 systematic review of polyphenol supplements in multiple sclerosis. The immune disease damages nerves in 2.9 million people worldwide, and current immune drugs protect nerves only partly while causing side effects.
Three databases and a trial registry were searched in June 2025, yielding 13 eligible trials with 785 patients in total. A nano form of curcumin improved disability scores across three small trials, while green tea extract, milk thistle, cranberry, and another curcumin form showed no clear gains. Harms stayed mild overall. Mixed study quality left proof at a moderate certainty level for most outcomes assessed.
Catalog record
| CREATOR | Lauren Brooks, Aqif Farhan bin Azmil Farid, Amudha Poobalan, Alexandra Johnstone, Phyo Kyaw Myint |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41258 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |