Beneficial Effects of Spermidine on Ovarian Function, Gut Microbiota Composition, and Associated Metabolic Changes
Chengweng Ji, Dongmei Jiang, Yunxuan Wu, Jue Huang, Yuxin Qi, Xin Wang, Weijie Zhang, Shuo Li, Lu Lu, Mingzhou Li, Bo Kang · 2026
Read Beneficial Effects of Spermidine on Ovarian Function, Gut Microbiota Composition, and Associated Metabolic Changes by Chengweng Ji, Dongmei Jiang, Yunxuan Wu, Jue Huang, Yuxin Qi, Xin Wang, Weijie Zhang, Shuo Li, Lu Lu, Mingzhou Li, Bo Kang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13304755.txt.
Description
Chengweng Ji and co-authors feed mice spermidine, a compound rich in wheat germ, and track fertility effects in a 2026 study. The chemical supports cell upkeep and egg development, but food-based effects on ovaries were untested.
Diets with graded spermidine doses raised its uptake and reshaped related compounds in the gut. Low-dose feeding lifted litter size and raised several fertility hormones in the blood. Ovaries held larger reserves with fewer dying follicles. Chemical and microbe profiling tied the gains to fat metabolism, hormone pathways, and shifts in gut bacteria makeup.
Catalog record
| CREATOR | Chengweng Ji, Dongmei Jiang, Yunxuan Wu, Jue Huang, Yuxin Qi, Xin Wang, Weijie Zhang, Shuo Li, Lu Lu, Mingzhou Li, Bo Kang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46322 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |