Spatial Immunology in Translation: Linking Immune Organisation to Therapeutic Outcome
Caio Santos Bonilha · 2026
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Description
Caio Santos Bonilha argues in a 2026 review that where immune activity sits inside tissue matters as much as which molecules are involved. Immune drugs are usually judged cell by cell, yet inflammation gathers in lasting pockets within diseased organs.
Cell mix, tissue compartments, and the staying power of contact zones shape where signals concentrate and persist. Reading these interaction zones as working units helps explain why the same drug engages its target well in one patient and poorly in another. Aligning drug plans with the immune layout that dominates a tissue may sharpen treatment choices.
Catalog record
| CREATOR | Caio Santos Bonilha |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34133 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |