Screening of a 4-Ethylguaiacol-Producing Bacillus coagulans JN11 and Biochemical Characterization of Its Phenolic Acid Decarboxylase BcPAD
Yufeng Liu, Hao Wang, Xinyue Lan, Rui Wang, Can Liu, Jun Liu, He Zou, Siqi Yuan · 2026
Read Screening of a 4-Ethylguaiacol-Producing Bacillus coagulans JN11 and Biochemical Characterization of Its Phenolic Acid Decarboxylase BcPAD by Yufeng Liu, Hao Wang, Xinyue Lan, Rui Wang, Can Liu, Jun Liu, He Zou, Siqi Yuan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13304128.txt.
Description
Yufeng Liu and co-authors hunt brewing microbes that make a smoky aroma compound in a 2026 screening study. The compound, 4-ethylguaiacol, gives fermented foods and Baijiu liquor prized woody and spicy notes.
Isolates from Baijiu pit mud yielded a Bacillus coagulans strain, JN11, that produced the aroma in sorghum juice. Its key enzyme gene was copied and grown in lab bacteria for testing. The enzyme worked best at mild acidity and moderate heat, liked one starting acid far above others, and gained activity with iron while zinc blocked it. Shape modeling hints why the favored acid fits so well.
Catalog record
| CREATOR | Yufeng Liu, Hao Wang, Xinyue Lan, Rui Wang, Can Liu, Jun Liu, He Zou, Siqi Yuan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41845 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |