TyG Index and Frailty as Composite Biomarkers of Cardiometabolic Risk and Mortality Across CKM Stages 0–3
Yaocheng Luo, Peng Zeng, Shuoya Huang, Zhenzhen Peng, Jian Zheng, Zumin Shi, Manoj Sharma, Yong Zhao · 2026
Read TyG Index and Frailty as Composite Biomarkers of Cardiometabolic Risk and Mortality Across CKM Stages 0–3 by Yaocheng Luo, Peng Zeng, Shuoya Huang, Zhenzhen Peng, Jian Zheng, Zumin Shi, Manoj Sharma, Yong Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13302982.txt.
Description
Blending a metabolism score with a frailty count sharpens risk forecasts in early cardiometabolic disease, Yaocheng Luo and colleagues report in a 2026 cohort analysis. Data from China's CHARLS and America's Health and Retirement Study covered people at CKM stages zero through three. Their combined triglyceride-glucose-frailty index was tested against later heart events and death.
Risk climbed steadily across index quarters in a dose-response pattern, bending twice along the way. The pattern held across subgroups, and the index sorted future cases with moderate accuracy in both cohorts. The authors offer it as a supporting gauge for sorting risk in early to mid stages, while calling for more checks on its clinical worth.
Catalog record
| CREATOR | Yaocheng Luo, Peng Zeng, Shuoya Huang, Zhenzhen Peng, Jian Zheng, Zumin Shi, Manoj Sharma, Yong Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30672 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |