From Discovery to Manufacturing: A Quantitative Review of Phosphonates and Strategies for High-Titer Production
Xinping Zhong, Biwei Song, Lixin Zhang, Tom Hsiang, Liming Ouyang, Jingyu Zhang · 2026
Read From Discovery to Manufacturing: A Quantitative Review of Phosphonates and Strategies for High-Titer Production by Xinping Zhong, Biwei Song, Lixin Zhang, Tom Hsiang, Liming Ouyang, Jingyu Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13302981.txt.
Description
Xinping Zhong and five co-authors published a review in 2026 on phosphonates, natural products defined by a stable carbon-phosphorus bond. Most of these compounds come from bacteria. They have a wide range of biological activities, which gives them potential uses in medicine and agriculture.
The review brings together 71 reports of these products published between 1959 and the present. The authors compare how the compounds were discovered, what activities they show, and which organisms produce them. They also summarize structure-activity relationships, meaning how a compound's structure affects what it does. A final section covers methods for raising production yields, including metabolic engineering and synthetic biology. It also suggests directions for finding new compounds of this kind and producing them at larger scale.
Catalog record
| CREATOR | Xinping Zhong, Biwei Song, Lixin Zhang, Tom Hsiang, Liming Ouyang, Jingyu Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |