Comment on Lee et al. Conservative Treatment with Teriparatide Versus Vertebroplasty for Acute Osteoporotic Vertebral Compression Fractures: A Meta-Analysis. J. Clin. Med. 2025, 14, 3967
In-Suk Bae · 2026
Read Comment on Lee et al. Conservative Treatment with Teriparatide Versus Vertebroplasty for Acute Osteoporotic Vertebral Compression Fractures: A Meta-Analysis. J. Clin. Med. 2025, 14, 3967 by In-Suk Bae (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13302713.txt.
Description
Praise mixed with pointed caveats fills a 2026 comment by In-Suk Bae on a meta-analysis of spine fracture treatment. Lee and colleagues had compared teriparatide drug therapy against vertebroplasty for acute osteoporotic vertebral compression fractures, crediting the drug with better long-term pain relief, bone density, and fewer new fractures. Bae congratulates them on the first such pooled comparison.
The comment then lists the soft spots: only five studies and 326 patients, heavy statistical heterogeneity, and the exclusion of kyphoplasty, a sibling cement procedure. Cost and the burden of daily injections also went unexamined. Bae calls for large multicenter trials with standardized protocols before practice shifts.
Catalog record
| CREATOR | In-Suk Bae |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4083 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |