Advances in GelMA Hydrogel-Enabled Angiogenic–Osteogenic Coupling: From Structural Programming to Exogenous Cue Synergy
Chenyujun Hu, Meng Zhang, Haoran Jiang, Yang Qu, Qi Meng, Jinqiu Tian, Hanran Zhang, Zhixiang Yang, Zhihao Lin, Bohan Xing, Peixun Zhang · 2026
Read Advances in GelMA Hydrogel-Enabled Angiogenic–Osteogenic Coupling: From Structural Programming to Exogenous Cue Synergy by Chenyujun Hu, Meng Zhang, Haoran Jiang, Yang Qu, Qi Meng, Jinqiu Tian, Hanran Zhang, Zhixiang Yang, Zhihao Lin, Bohan Xing, Peixun Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13302648.txt.
Description
Chenyujun Hu and co-authors review, in a 2026 paper, hydrogel materials designed to grow blood vessels and bone together during repair. Bone healing fails when vessel growth lags, a coupling that weakens with age, poor circulation, and chronic inflammation. The gel, called GelMA, mimics natural tissue matrix and can be shaped by three-dimensional printing.
Strategies are sorted into three families: building guidance into the material itself, delivering active cargo such as growth factors and cells, and making gels that respond to local signals. Delivery systems hold the strongest early evidence, while built-in designs may prove easier to manufacture consistently. Responsive systems remain mostly small-animal experiments. The authors urge simpler, reproducible designs over added complexity.
Catalog record
| CREATOR | Chenyujun Hu, Meng Zhang, Haoran Jiang, Yang Qu, Qi Meng, Jinqiu Tian, Hanran Zhang, Zhixiang Yang, Zhihao Lin, Bohan Xing, Peixun Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |