Rethinking Oxidative Stress in Helicobacter pylori: A Multidisciplinary Framework Linking Redox Signaling, Cellular Reprogramming, and Diagnostic Precision in Gastric Carcinogenesis
Ayman Elbehiry, Adil Abalkhail, Sulaiman Anagreyyah, Suha Anjiria, Majed Aljahdali, Mamdouh Alharbi, Naif Almutairi, Mohammed Althagafi, Husam M. Edrees, Abdulaziz M. Almuzaini, Ihab M. Moussa, Saud Alhamyani, Abdulrahman Almaliki, Eman Marzouk · 2026
Read Rethinking Oxidative Stress in Helicobacter pylori: A Multidisciplinary Framework Linking Redox Signaling, Cellular Reprogramming, and Diagnostic Precision in Gastric Carcinogenesis by Ayman Elbehiry, Adil Abalkhail, Sulaiman Anagreyyah, Suha Anjiria, Majed Aljahdali, Mamdouh Alharbi, Naif Almutairi, Mohammed Althagafi, Husam M. Edrees, Abdulaziz M. Almuzaini, Ihab M. Moussa, Saud Alhamyani, Abdulrahman Almaliki, Eman Marzouk (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13302125.txt.
Description
Ayman Elbehiry and a broad team reframe, in a 2026 review, how stomach infection with Helicobacter pylori can progress toward cancer through oxidative stress. This bacterium is a leading cause of stomach cancer worldwide, yet the chain from long-term infection to cancer remains only partly mapped. Earlier reviews often treated oxygen-linked damage on its own.
The proposed model ties that damage to inflamed signalling, failing cell powerhouses, shifts in energy use, and changes in gene control. Six major pathways, including NF-kB and STAT3, act as joint drivers of cell survival and unstable genes. A threshold model describes how early stress hardens into stable cancer-promoting change. The authors also weigh new tests, from markers of that damage to AI-assisted tissue review, and argue for treatments matched to disease stage.
Catalog record
| CREATOR | Ayman Elbehiry, Adil Abalkhail, Sulaiman Anagreyyah, Suha Anjiria, Majed Aljahdali, Mamdouh Alharbi, Naif Almutairi, Mohammed Althagafi, Husam M. Edrees, Abdulaziz M. Almuzaini, Ihab M. Moussa, Saud Alhamyani, Abdulrahman Almaliki, Eman Marzouk |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |