Longitudinal Assessment of Joint Health in Paediatric Haemophilia Using the HEAD-US Ultrasound Scoring System: The ULTRA Study
Aikaterini Michalopoulou, Olympia Papakonstantinou, Athina Dettoraki, Dimitrios Syrengelas, Vassiliki Bizimi, Konstantina Dakou, Miltiades Kyprianou, Vassiliki Spoulou, Helen Pergantou, Christina Kanaka-Gantenbein · 2026
Read Longitudinal Assessment of Joint Health in Paediatric Haemophilia Using the HEAD-US Ultrasound Scoring System: The ULTRA Study by Aikaterini Michalopoulou, Olympia Papakonstantinou, Athina Dettoraki, Dimitrios Syrengelas, Vassiliki Bizimi, Konstantina Dakou, Miltiades Kyprianou, Vassiliki Spoulou, Helen Pergantou, Christina Kanaka-Gantenbein (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13300941.txt.
Description
Aikaterini Michalopoulou and co-authors track joint health in Greek children with hemophilia using ultrasound in the ULTRA study, reported in 2026. Repeated joint bleeds can cripple, and the HEAD-US ultrasound score promises earlier warning than hands-on examination. Forty-seven boys aged five to eighteen, most with severe disease and all on preventive factor treatment, were scored at baseline. They were scored again across scheduled follow-up visits stretching to three years, alongside clinical joint scores and quality of life measures.
Baseline ultrasound scores were low and barely budged overall, though the left knee improved significantly. Ankles consistently scored worst among joints. Inflamed joint lining was the commonest finding, while cartilage damage stayed rare and bone change almost absent. Ultrasound flagged more abnormalities than the clinical score did. With follow-up incomplete for many children, the authors still endorse routine ultrasound monitoring as the more sensitive early warning tool.
Catalog record
| CREATOR | Aikaterini Michalopoulou, Olympia Papakonstantinou, Athina Dettoraki, Dimitrios Syrengelas, Vassiliki Bizimi, Konstantina Dakou, Miltiades Kyprianou, Vassiliki Spoulou, Helen Pergantou, Christina Kanaka-Gantenbein |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |