Sex differences after atrial fibrillation ablation: a patient level meta-analysis

L Barbosa, A Rivera, V M R Oliveira, R L Miranda, B Araujo, J R G Costa, L Tartuce, C Pisani, M I Scanavacca, F Darrieux, J Brugada, B R Nascimento, M C P Nunes, R Mehran · 2026

Read Sex differences after atrial fibrillation ablation: a patient level meta-analysis by L Barbosa, A Rivera, V M R Oliveira, R L Miranda, B Araujo, J R G Costa, L Tartuce, C Pisani, M I Scanavacca, F Darrieux, J Brugada, B R Nascimento, M C P Nunes, R Mehran (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13300672.txt.

Description

L Barbosa and a large co-author team pool patient level data on sex differences after atrial fibrillation ablation in a 2026 meta-analysis. Earlier studies hinted that women relapse more often than men, but the size and timing of the gap were unclear. The team searched three databases, reconstructed individual patient data from published survival curves in forty-three studies, and modeled recurrence risk over follow-up stretching to twenty years.

The combined cohort held 144,610 patients, about thirty-five percent women, who started older and with more hypertension, thyroid trouble, and valve disease than the men. Across follow-up, women carried a thirteen percent higher relative risk of recurrence after ablation. The authors say the gap is real and consistent enough to matter in practice. They recommend that sex inform risk discussions and follow-up planning after ablation rather than being treated as background noise.

Catalog record

CREATORL Barbosa, A Rivera, V M R Oliveira, R L Miranda, B Araujo, J R G Costa, L Tartuce, C Pisani, M I Scanavacca, F Darrieux, J Brugada, B R Nascimento, M C P Nunes, R Mehran
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13300672

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