Chronic Exposure to Gelsemium Preparations Alters Mitochondrial Bioenergetics, Neurite Outgrowth, and Akt/mTOR Signaling in Human Neuronal Cells
Imane Lejri, Amandine Grimm, Pascal Trempat, Stephanie Chanut, Naoual Boujedaini, Anne Eckert · 2026
Read Chronic Exposure to Gelsemium Preparations Alters Mitochondrial Bioenergetics, Neurite Outgrowth, and Akt/mTOR Signaling in Human Neuronal Cells by Imane Lejri, Amandine Grimm, Pascal Trempat, Stephanie Chanut, Naoual Boujedaini, Anne Eckert (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13300635.txt.
Description
Long exposure to homeopathic Gelsemium dilutions changed how cultured human nerve cells handle energy, Imane Lejri and colleagues report in a 2026 lab study. SH-SY5Y cells were kept for fourteen days with mixes diluted to 9C, 15C, and 30C strength. The team measured cell breathing, oxidant levels, survival, neurite growth, and two signaling proteins.
Treated cells made more ATP and drew more oxygen than untreated controls, while oxidant stress fell. They also survived better and grew longer neurites. Two switch proteins, Akt and mTOR, carried more phosphate tags, hinting at one shared control path behind the changes. The authors frame the work as early groundwork for studying stress-linked brain disorders in a dish.
Catalog record
| CREATOR | Imane Lejri, Amandine Grimm, Pascal Trempat, Stephanie Chanut, Naoual Boujedaini, Anne Eckert |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44227 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |