Adipokine profile in acute heart failure: associations with natriuretic response and prognosis
Jan Biegus, Rafał Tymków, Gracjan Iwanek, Robert Zymliński, Mateusz Guzik, Magdalena Hurkacz, Wojciech Sopyla, Piotr Gajewski, Piotr Ponikowski · 2026
Read Adipokine profile in acute heart failure: associations with natriuretic response and prognosis by Jan Biegus, Rafał Tymków, Gracjan Iwanek, Robert Zymliński, Mateusz Guzik, Magdalena Hurkacz, Wojciech Sopyla, Piotr Gajewski, Piotr Ponikowski (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13298864.txt.
Description
Jan Biegus and co-authors link fat tissue signals to diuretic response and outcomes in acute heart failure, in a 2026 study. Water pills must clear fluid fast when the heart fails suddenly. The urine sodium level after a dose shows how well that clearing works. Fat tissue sends hormone-like signals called adipokines. Their role in acute episodes was unclear.
The study followed more than two hundred patients treated for acute heart failure. Blood adipokine profiles were matched with urine sodium two hours after dosing. Links to later outcomes were also tested. Some signals tracked with weaker diuretic response. Such markers could flag patients who need stronger therapy early. The work joins metabolism research with front-line heart failure care.
Catalog record
| CREATOR | Jan Biegus, Rafał Tymków, Gracjan Iwanek, Robert Zymliński, Mateusz Guzik, Magdalena Hurkacz, Wojciech Sopyla, Piotr Gajewski, Piotr Ponikowski |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |