Association Between Early and Long-Term Changes in Liver Stiffness in Patients with MASLD Undergoing Serial Magnetic Resonance Elastography

Shohei Kimura, Yutaka Yasui, Nobuharu Tamaki, Mayu Higuchi, Takuya Shima, Mina Taguchi, Yudai Yamazaki, Risa Seike, Naoki Uchihara, Yuki Tanaka, Ryohei Kobayashi, Junko Yagita, Yuka Kasano, Yasuyuki Komiyama, Kenta Takaura, Hitomi Takada, Shohei Tanaka, Chiaki Maeyashiki, Yuka Takahashi, Hiroyuki Nakanishi, Kaoru Tsuchiya, Namiki Izumi, Masayuki Kurosaki · 2026

Read Association Between Early and Long-Term Changes in Liver Stiffness in Patients with MASLD Undergoing Serial Magnetic Resonance Elastography by Shohei Kimura, Yutaka Yasui, Nobuharu Tamaki, Mayu Higuchi, Takuya Shima, Mina Taguchi, Yudai Yamazaki, Risa Seike, Naoki Uchihara, Yuki Tanaka, Ryohei Kobayashi, Junko Yagita, Yuka Kasano, Yasuyuki Komiyama, Kenta Takaura, Hitomi Takada, Shohei Tanaka, Chiaki Maeyashiki, Yuka Takahashi, Hiroyuki Nakanishi, Kaoru Tsuchiya, Namiki Izumi, Masayuki Kurosaki (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13298384.txt.

Description

Early softening of a stiff fatty liver tends to continue, show Shohei Kimura and co-authors in a 2026 imaging study. They followed 100 patients with metabolic liver disease who had magnetic resonance elastography at baseline, about one year, and about three years.

Twenty-two patients counted as early responders, meaning liver stiffness had dropped at least 19% by the second scan. Those patients were far more likely to keep that improvement at year three, 59% versus 27% for the rest, and the link held after adjustment with an odds ratio of 3.41. Stiffer livers at baseline also improved more often. The authors say short-term scans can hint at the longer trajectory.

Catalog record

CREATORShohei Kimura, Yutaka Yasui, Nobuharu Tamaki, Mayu Higuchi, Takuya Shima, Mina Taguchi, Yudai Yamazaki, Risa Seike, Naoki Uchihara, Yuki Tanaka, Ryohei Kobayashi, Junko Yagita, Yuka Kasano, Yasuyuki Komiyama, Kenta Takaura, Hitomi Takada, Shohei Tanaka, Chiaki Maeyashiki, Yuka Takahashi, Hiroyuki Nakanishi, Kaoru Tsuchiya, Namiki Izumi, Masayuki Kurosaki
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23141
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13298384

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