Safety Assessment of Aspergillus cristatus CCNH008 for Potential Use in Food and Health Applications

Zishan Jiao, Jiahao Huang, Juan Yang, Xinyi Chen, Xiaowei Zheng · 2026

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Description

Zishan Jiao and colleagues assess the safety of a tea-fermenting fungus strain for possible food use, in a 2026 toxicology study. Aspergillus cristatus drives Fu brick tea fermentation, yet strain-level safety data remain limited. Their strain, CCNH008, underwent acute and ninety-day feeding studies in rodents, plus a recovery period and several genotoxicity tests.

No deaths, clinical signs, or treatment-related tissue changes appeared at the doses tested, and body weight, blood measures, and organ weights stayed unaffected. Mutation and chromosome damage assays were negative throughout. The authors conclude the strain shows no evidence of oral toxicity or genotoxicity, supporting further food application work.

Catalog record

CREATORZishan Jiao, Jiahao Huang, Juan Yang, Xinyi Chen, Xiaowei Zheng
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13298308

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