Autoimmune Hepatitis Induced by Immune Checkpoint Inhibitors in Adults: A Systematic Review
Sarita Chonat, Jonathan Soldera · 2026
Read Autoimmune Hepatitis Induced by Immune Checkpoint Inhibitors in Adults: A Systematic Review by Sarita Chonat, Jonathan Soldera (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13298183.txt.
Description
Cancer immunotherapy sometimes inflames the liver in a pattern resembling autoimmune hepatitis, and Sarita Chonat with Jonathan Soldera reviewed the published cases in 2026. They searched for reports of this injury after immune checkpoint inhibitors and gathered diagnosis, treatment, and outcome details.
Twenty-two studies covered 195 patients. Steroids were the main first treatment, with recovery in 102 of 105 patients treated with steroids alone, and mycophenolate rescued most steroid-resistant cases. The cancer drug was stopped in 141 patients, and 55 were later rechallenged without the liver problem returning in the records reviewed. Nineteen patients recovered with no drug treatment at all.
Catalog record
| CREATOR | Sarita Chonat, Jonathan Soldera |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54448 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |