Serum Interleukin-6 as an Inflammatory Biomarker Associated with HBV Viral Load in HBsAg-Positive Chronic Hepatitis B

Jayakrishna Pamarthi, Sugan Panneerselvam, Nanda Amarnath Rajesh, Venkataratna Bharat Gangireddy, Mohanram Murugan, Leela Kakithara Vajaravelu, Jayaprakash Thulukanam, Mansour Alanazi, Janardanan Subramonia Kumar · 2026

Read Serum Interleukin-6 as an Inflammatory Biomarker Associated with HBV Viral Load in HBsAg-Positive Chronic Hepatitis B by Jayakrishna Pamarthi, Sugan Panneerselvam, Nanda Amarnath Rajesh, Venkataratna Bharat Gangireddy, Mohanram Murugan, Leela Kakithara Vajaravelu, Jayaprakash Thulukanam, Mansour Alanazi, Janardanan Subramonia Kumar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13298012.txt.

Description

An inflammatory signal in the blood rises in step with hepatitis B virus levels, report Jayakrishna Pamarthi and co-authors in a 2026 hospital study. They measured interleukin-6 and viral DNA in 293 patients who tested positive for the hepatitis B surface antigen.

IL-6 climbed significantly across viral load categories and ran higher in patients positive for the e antigen, while showing no pattern by age, sex, or cirrhosis. Its correlation with viral DNA was r = 0.40, and regression kept viral load as the independent predictor of IL-6. Links to ordinary liver injury markers were weaker, leading the authors to propose IL-6 as a supporting marker of disease activity.

Catalog record

CREATORJayakrishna Pamarthi, Sugan Panneerselvam, Nanda Amarnath Rajesh, Venkataratna Bharat Gangireddy, Mohanram Murugan, Leela Kakithara Vajaravelu, Jayaprakash Thulukanam, Mansour Alanazi, Janardanan Subramonia Kumar
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23843
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13298012

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