ZEB1 Modifies VE‐Cadherin Signaling in Lymphatic Endothelial Cells
Nada S Ahmed, Joseph L Horder, Charles T Cresswell, Poppy E Harris, Amy P Lynch, Zarah B Tabrizi, Kathryn R Green, James H Hallwood, Anton C Smith, Michael A Portelli, Alexander J Fezovich, Christos Spanos, David S Gardner, Alan McIntyre, Sarah J Storr, Daniel G Booth, David O Bates, Andrew V Benest · 2026
Read ZEB1 Modifies VE‐Cadherin Signaling in Lymphatic Endothelial Cells by Nada S Ahmed, Joseph L Horder, Charles T Cresswell, Poppy E Harris, Amy P Lynch, Zarah B Tabrizi, Kathryn R Green, James H Hallwood, Anton C Smith, Michael A Portelli, Alexander J Fezovich, Christos Spanos, David S Gardner, Alan McIntyre, Sarah J Storr, Daniel G Booth, David O Bates, Andrew V Benest (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13297878.txt.
Description
Cutting one gene weakens the seals in lymph vessel walls, Nada S Ahmed and her team report in a 2026 cell study. The gene, ZEB1, is known for guiding cell change in other tissues. Its role in the lymph system was not mapped.
The team read both protein and gene data from lymph vessel cells. Cells that lost ZEB1 showed less of a key mark on VE-cadherin, the glue protein at cell seams. The cell sheet leaked more, and white blood cells crossed it more freely. Loss of ZEB1 also cut the kinase YES and shifted YAP1, and muting YAP1 alone copied much of the leak. The work ties ZEB1 to the upkeep of lymph vessel walls.
Catalog record
| CREATOR | Nada S Ahmed, Joseph L Horder, Charles T Cresswell, Poppy E Harris, Amy P Lynch, Zarah B Tabrizi, Kathryn R Green, James H Hallwood, Anton C Smith, Michael A Portelli, Alexander J Fezovich, Christos Spanos, David S Gardner, Alan McIntyre, Sarah J Storr, Daniel G Booth, David O Bates, Andrew V Benest |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48475 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |