Inflammation in Cardiomyopathies: Cellular Mechanisms Across Cardiac Phenotype
Antonio Lattanzio, Giulia Marchionni, Giulia Pecci, Federico Ciccarelli, Silvia Stavagna, Jacopo Costantino, Federico Ballatore, Maria Alfarano, Francesco Ciciarello, Cristina Chimenti · 2026
Read Inflammation in Cardiomyopathies: Cellular Mechanisms Across Cardiac Phenotype by Antonio Lattanzio, Giulia Marchionni, Giulia Pecci, Federico Ciccarelli, Silvia Stavagna, Jacopo Costantino, Federico Ballatore, Maria Alfarano, Francesco Ciciarello, Cristina Chimenti (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13297474.txt.
Description
Heart muscle diseases are often blamed on genes or on wear and tear. A 2026 review by Antonio Lattanzio and his team makes the case that immune attack plays a core role too. They pulled proof from five diseases, from thick-heart and loose-heart forms to Fabry disease and amyloid buildup.
Each disease starts with a unlike trigger: stored fats, misfolded protein, strain, or bits of virus. All of them switch on the same immune paths, through Toll-like receptors, NF-κB, and the NLRP3 inflammasome. The immune fire then drives scar tissue and stiff walls. If that shared path holds, drugs that calm the immune system could help across all five diseases.
Catalog record
| CREATOR | Antonio Lattanzio, Giulia Marchionni, Giulia Pecci, Federico Ciccarelli, Silvia Stavagna, Jacopo Costantino, Federico Ballatore, Maria Alfarano, Francesco Ciciarello, Cristina Chimenti |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43442 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |