Anakinra in a Preterm Infant with Bronchopulmonary Dysplasia: A Case Report
Simona Fattore, Chiara Tirone, Alessandro Perri, Francesca Paola Fusco, Simonetta Frezza, Milena Tana, Donato Rigante, Davide De Tomaso, Nicoletta Menzella, Alessandra Lio, Francesca Serrao, Stefano Nobile, Andrea Piras, Silvia Baroni, Simonetta Costa, Giovanni Vento · 2026
Read Anakinra in a Preterm Infant with Bronchopulmonary Dysplasia: A Case Report by Simona Fattore, Chiara Tirone, Alessandro Perri, Francesca Paola Fusco, Simonetta Frezza, Milena Tana, Donato Rigante, Davide De Tomaso, Nicoletta Menzella, Alessandra Lio, Francesca Serrao, Stefano Nobile, Andrea Piras, Silvia Baroni, Simonetta Costa, Giovanni Vento (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13297449.txt.
Description
Simona Fattore and a large team report giving anakinra, a drug that blocks the inflammation signal IL-1, to a preterm baby with chronic lung disease, in a 2026 case report. The girl was born at twenty-eight weeks weighing 800 grams and stayed on breathing support for months. Standard care failed to settle her lungs, so off-label treatment began at 150 days of life, injected under the skin twice daily.
Her breathing then eased step by step. Oxygen needs and airway pressure fell, and support stepped down through three gentler forms until discharge on minimal help. Spit tests tracked inflammation without blood draws, and one marker fell steadily. The drug was well tolerated. The authors caution that natural recovery may share the credit.
Catalog record
| CREATOR | Simona Fattore, Chiara Tirone, Alessandro Perri, Francesca Paola Fusco, Simonetta Frezza, Milena Tana, Donato Rigante, Davide De Tomaso, Nicoletta Menzella, Alessandra Lio, Francesca Serrao, Stefano Nobile, Andrea Piras, Silvia Baroni, Simonetta Costa, Giovanni Vento |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |