The Exchangeable Copper–Zinc Ratio Links Sex Hormones, Tumor Burden, and Epithelial Remodeling in Colorectal Cancer
Rosanna Squitti, Anastasia De Luca, Altea Severino, Gianluca Rizzo, Luca Emanuele Amodio, Federica Marzi, Gabriella Vicano, Mauro Cozzolino, Angela Lombardi, Mauro Rongioletti, Vincenzo Tondolo · 2026
Read The Exchangeable Copper–Zinc Ratio Links Sex Hormones, Tumor Burden, and Epithelial Remodeling in Colorectal Cancer by Rosanna Squitti, Anastasia De Luca, Altea Severino, Gianluca Rizzo, Luca Emanuele Amodio, Federica Marzi, Gabriella Vicano, Mauro Cozzolino, Angela Lombardi, Mauro Rongioletti, Vincenzo Tondolo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13297341.txt.
Description
Rosanna Squitti and co-authors study, in 2026, copper-zinc imbalance in bowel cancer, focusing on the loose, active fraction of copper rather than the total. Blood metals, sex hormones and tumour proteins were measured in 152 patients and 140 healthy controls, split by sex.
Patients carried more copper, less zinc and a sharply higher active-copper ratio. That ratio tracked with tumour size and stage, more with size in women and spread in men, and with tissue shifts marking cells loosening their epithelial character. The authors propose the ratio as an informative marker needing validation.
Catalog record
| CREATOR | Rosanna Squitti, Anastasia De Luca, Altea Severino, Gianluca Rizzo, Luca Emanuele Amodio, Federica Marzi, Gabriella Vicano, Mauro Cozzolino, Angela Lombardi, Mauro Rongioletti, Vincenzo Tondolo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39607 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |