Alternative Splicing in Human Viral Oncogenesis and Tumor Progression
Ilaria Martelli, Lucia Annamaria Cappabianca, Paola Cipriani, Antonietta Rosella Farina, Maddalena Sbaffone, Andrew Reay Mackay · 2026
Read Alternative Splicing in Human Viral Oncogenesis and Tumor Progression by Ilaria Martelli, Lucia Annamaria Cappabianca, Paola Cipriani, Antonietta Rosella Farina, Maddalena Sbaffone, Andrew Reay Mackay (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13297286.txt.
Description
Ilaria Martelli and co-authors review, in 2026, how cancer-causing viruses corrupt RNA splicing, the editing step that decides which protein versions cells build. Nine viruses are classed as proven human carcinogens, blamed for a large share of cancers worldwide.
By hijacking splicing machinery, these viruses force out abnormal proteins, some directly cancer-driving, touching growth, spread and treatment resistance from first change to metastasis. The mechanism stays underappreciated beside better-known tricks such as disabling tumour suppressors. The authors argue fixing virus-skewed splicing opens fresh therapeutic chances that are worth pursuing further.
Catalog record
| CREATOR | Ilaria Martelli, Lucia Annamaria Cappabianca, Paola Cipriani, Antonietta Rosella Farina, Maddalena Sbaffone, Andrew Reay Mackay |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 96065 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |