Reduction in Wearable-Derived Maximal Oxygen Consumption (VO₂max) During Tamsulosin Use in an Endurance Athlete
Hunter Cohn, Ava Zamani, Michael Sessine, Michael L Cher · 2026
Read Reduction in Wearable-Derived Maximal Oxygen Consumption (VO₂max) During Tamsulosin Use in an Endurance Athlete by Hunter Cohn, Ava Zamani, Michael Sessine, Michael L Cher (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13297262.txt.
Description
Hunter Cohn and colleagues describe an endurance athlete whose watch-estimated aerobic capacity fell after starting a prostate drug in a 2026 case report. The runner began tamsulosin for urinary symptoms, then noticed training felt harder. Smartwatch records from 113 outdoor runs were compared across periods before, during, and after the drug.
Estimated maximal oxygen uptake dropped clearly during daily tamsulosin use. The decline also appeared when runs at similar paces were compared, reducing the chance that easier training explained it. After switching to tadalafil, the estimate recovered only partly. One case cannot prove cause, and the authors ask for larger controlled studies of alpha-blocker effects on exercise capacity.
Catalog record
| CREATOR | Hunter Cohn, Ava Zamani, Michael Sessine, Michael L Cher |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |