Betanin from Beta vulgaris Attenuates Complete Freund’s Adjuvant-Induced Inflammatory Pain: Integrated Preclinical and In Silico Insights
Ahmed Massoud, Amina E. Essawy, Mohammed A. Alfredan, Ashraf M. Abdel-Moneim, Rehab A. Gomaa, Sherine Abdel Salam · 2026
Read Betanin from Beta vulgaris Attenuates Complete Freund’s Adjuvant-Induced Inflammatory Pain: Integrated Preclinical and In Silico Insights by Ahmed Massoud, Amina E. Essawy, Mohammed A. Alfredan, Ashraf M. Abdel-Moneim, Rehab A. Gomaa, Sherine Abdel Salam (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13296267.txt.
Description
Ahmed Massoud and colleagues test betanin, the red pigment of beetroot, against inflammatory pain in rats, in a 2026 study. Betanin is known for fighting inflammation and oxidation, yet its pain-soothing power was little explored. Rats got a shot of complete Freund's adjuvant to spark lasting paw pain, then daily betanin by mouth for fourteen days at one of two doses.
Betanin cut paw swelling and raised the time rats bore a hot plate. In the spinal cord on the hurt side, both doses lifted an anti-inflammatory signal, while the higher dose also cut oxidative harm and a pro-inflammatory signal. Two small RNA switches moved in step with the chemistry, and microscope checks showed less nerve damage. Docking sums rounded out the case for the pigment as a pain candidate.
Catalog record
| CREATOR | Ahmed Massoud, Amina E. Essawy, Mohammed A. Alfredan, Ashraf M. Abdel-Moneim, Rehab A. Gomaa, Sherine Abdel Salam |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |