Deciphering Ultra-High Dose Rate Irradiation with Drosophila melanogaster
Marvin Kreuzer, Irene Vetrugno, Riccardo Dal Bello, Stephanie Tanadini-Lang, Erich Brunner, Darlina von Salis, Damian Manetsch, Sandipan Tewary, Matthias Guckenberger, Jamie Little, Martin Pruschy · 2026
Read Deciphering Ultra-High Dose Rate Irradiation with Drosophila melanogaster by Marvin Kreuzer, Irene Vetrugno, Riccardo Dal Bello, Stephanie Tanadini-Lang, Erich Brunner, Darlina von Salis, Damian Manetsch, Sandipan Tewary, Matthias Guckenberger, Jamie Little, Martin Pruschy (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13296059.txt.
Description
Ultra-fast radiation in fruit flies is tested in 2026 by Marvin Kreuzer and co-authors as a stand-in for studying the FLASH effect, where rapid dosing spares healthy tissue. A clinical accelerator was adapted to deliver electron beams at thousands of times the usual rate to adult female flies.
Flies given single high ultra-fast doses lived longer than those given standard-rate doses, and split ultra-fast doses helped further. Standard dosing at a lower level caused climbing problems that ultra-fast dosing did not. Signs of a damaging cell process appeared in brains only after standard dosing. The authors promote flies as a handy model for this puzzle.
Catalog record
| CREATOR | Marvin Kreuzer, Irene Vetrugno, Riccardo Dal Bello, Stephanie Tanadini-Lang, Erich Brunner, Darlina von Salis, Damian Manetsch, Sandipan Tewary, Matthias Guckenberger, Jamie Little, Martin Pruschy |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27697 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |