Mechano-immune interactions in musculoskeletal aging: Mechanisms and translational perspectives
Fulin Zhou, Xianglong Zhou, Jiheng Xiao, Jianhui Xiang, Yang Liu, Weicheng Chen, Hanhong Fang, Haoran Zhou, Xiao Lv, Liming Xiong · 2026
Read Mechano-immune interactions in musculoskeletal aging: Mechanisms and translational perspectives by Fulin Zhou, Xianglong Zhou, Jiheng Xiao, Jianhui Xiang, Yang Liu, Weicheng Chen, Hanhong Fang, Haoran Zhou, Xiao Lv, Liming Xiong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13295842.txt.
Description
Fulin Zhou and colleagues offer a 2026 review of how physical forces and the immune system interact as bones, joints and muscles age. The field, called mechano-immunology, asks how load and tissue stiffness shape immune cell behaviour.
With age, people move less, tissues stiffen and immune cells sense force less well, which weakens infection clearance and repair. The authors link that breakdown to osteoarthritis, osteoporosis and other wasting conditions. They also survey possible remedies, from exercise and controlled loading to engineered materials, that might restore balance in ageing musculoskeletal tissue.
Catalog record
| CREATOR | Fulin Zhou, Xianglong Zhou, Jiheng Xiao, Jianhui Xiang, Yang Liu, Weicheng Chen, Hanhong Fang, Haoran Zhou, Xiao Lv, Liming Xiong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 109657 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |