Ultra-high-field magnetic resonance imaging reveals sex-specific recovery after ischemic stroke following treatment with three-dimensional human mesenchymal stem cell–derived extracellular vesicles

Jamini Bhagu, Arshia Arbabian, Thurston Da Vitoria Lobo, Katherine Martinez, Dayna L Richter, Hannah Bryant, Malathy Elumalai, Yan Li, Samuel C Grant · 2026

Read Ultra-high-field magnetic resonance imaging reveals sex-specific recovery after ischemic stroke following treatment with three-dimensional human mesenchymal stem cell–derived extracellular vesicles by Jamini Bhagu, Arshia Arbabian, Thurston Da Vitoria Lobo, Katherine Martinez, Dayna L Richter, Hannah Bryant, Malathy Elumalai, Yan Li, Samuel C Grant (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13295759.txt.

Description

Jamini Bhagu and colleagues image stroke recovery by sex in a 2026 study. Stroke plays out differently in females and males, and stem cell vesicles grown in three-dimensional clusters may aid repair. Whether benefit differs by sex, tracked inside the living brain, needed testing with very strong scanners.

Labelled vesicles or salt water were delivered at vessel reopening in a temporary blockage model. Scans at extremely high field followed tissue, sodium, diffusion, and chemical changes over 21 days. Vesicle treatment trended toward smaller lesions, earlier sodium balance, and steadier brain chemicals, with females recovering somewhat better. Behaviour gaps stayed unclear.

Catalog record

CREATORJamini Bhagu, Arshia Arbabian, Thurston Da Vitoria Lobo, Katherine Martinez, Dayna L Richter, Hannah Bryant, Malathy Elumalai, Yan Li, Samuel C Grant
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE57633
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13295759

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