Characterization of Phenolic Profiles Using UPLC-Q-TOF-MS/MS and NMR in the Biofunctional Fraction of Korean Winter Spinach (Spinacia oleracea L.) Leaves: Evaluation of Major Phenolics and Their Bioactivities Under Optimized Extraction Conditions
Eun Young Seo, Eun Jeong Ko, Du Yong Cho, Ye Ri Jeong, Se Hyeon Jeon, Dong Hyun Park, Mu Yeun Jang, Jeong Yoon Kim, Kye Man Cho, Jin Hwan Lee · 2026
Read Characterization of Phenolic Profiles Using UPLC-Q-TOF-MS/MS and NMR in the Biofunctional Fraction of Korean Winter Spinach (Spinacia oleracea L.) Leaves: Evaluation of Major Phenolics and Their Bioactivities Under Optimized Extraction Conditions by Eun Young Seo, Eun Jeong Ko, Du Yong Cho, Ye Ri Jeong, Se Hyeon Jeon, Dong Hyun Park, Mu Yeun Jang, Jeong Yoon Kim, Kye Man Cho, Jin Hwan Lee (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13295262.txt.
Description
Eun Young Seo and colleagues squeeze Korean winter spinach for its most useful chemistry, in a 2026 study of the Allseason cultivar. Spinach leaves carry phenolic compounds with antioxidant and other protective effects, but earlier work profiled summer or greenhouse leaves with fewer tests. Using high-end mass spectrometry plus nuclear magnetic resonance to confirm structures, the team compared extraction solvents and conditions, then ran five different bioactivity assays on the extracts.
A half-methanol extract won, and patience paid off: seventy-two hours at mild warmth pulled out the richest levels of the three main flavone compounds. Twelve phenolics were identified in all. One isolated compound stood out as the strongest antioxidant in two radical tests, beating its siblings clearly. Statistical grouping separated the extracts cleanly by solvent strength. The authors pitch winter spinach as a nutraceutical source worth harvesting under tuned conditions.
Catalog record
| CREATOR | Eun Young Seo, Eun Jeong Ko, Du Yong Cho, Ye Ri Jeong, Se Hyeon Jeon, Dong Hyun Park, Mu Yeun Jang, Jeong Yoon Kim, Kye Man Cho, Jin Hwan Lee |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |