TAM-targeted nanomedicine in cancer: biological basis, therapeutic strategies, and translational perspectives
Lili Zhou, Fang Yuan, Yangyang Wu, Xin Li, Debiao Xiang · 2026
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Description
Lili Zhou and colleagues review nanomedicine aimed at tumour-associated macrophages in a 2026 article. These immune cells are the commonest immune type inside tumours and steer vessel growth, spread, immune escape, and drug resistance. New profiling work shows they vary far more than the old two-type scheme suggested.
Approaches are grouped by goal: blocking fresh macrophage arrival, removing tumour-helping cells, reprogramming them, or boosting their eating and immune signalling roles. Coated particles, cell membrane disguises, and vesicle platforms widen the design menu. The authors weigh trial progress against hurdles in targeting accuracy, stray effects on healthy macrophages, and large-scale making.
Catalog record
| CREATOR | Lili Zhou, Fang Yuan, Yangyang Wu, Xin Li, Debiao Xiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 110415 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |