Research Progress and Application Prospects of Bioaffinity Chromatography in Screening Cardiotoxic Components of Chinese Herbal Medicines
Huimin Lin, Jiaxuan Zhu, Leyao Xian, Hongjin Chen, Dawei Zou, Jingdan Zhang, Xiuye Huang, Yufeng Huang, Fan He · 2026
Read Research Progress and Application Prospects of Bioaffinity Chromatography in Screening Cardiotoxic Components of Chinese Herbal Medicines by Huimin Lin, Jiaxuan Zhu, Leyao Xian, Hongjin Chen, Dawei Zou, Jingdan Zhang, Xiuye Huang, Yufeng Huang, Fan He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13294911.txt.
Description
Huimin Lin and a large team review a screening approach for heart-harming ingredients in Chinese herbal medicines in a 2026 article. Some herbs long viewed as safe can still damage the heart, often without warning. Bioaffinity chromatography, which fishes out compounds that bind chosen biological targets, may catch such risks earlier.
Known harm routes include disturbed heart ion channels, damaged mitochondria, cell death, and metabolic upset. Five forms of the technique are explained, from antibody and lectin columns to cell membrane and receptor based versions. The authors propose using binding based screening for early warning and mechanism work, shifting safety checks from reaction after harm to prediction beforehand.
Catalog record
| CREATOR | Huimin Lin, Jiaxuan Zhu, Leyao Xian, Hongjin Chen, Dawei Zou, Jingdan Zhang, Xiuye Huang, Yufeng Huang, Fan He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32977 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |