Utility of miRNA biomarkers in patients with acute myocardial infarction (UNIAMI)—results from a prospective pilot study
Chakradhara Rao S. Uppugunduri, Koustav Sarkar, Oishi Mukherjee, Kaviya Manoharan, Iyshwarya B. K, Melvin George · 2026
Read Utility of miRNA biomarkers in patients with acute myocardial infarction (UNIAMI)—results from a prospective pilot study by Chakradhara Rao S. Uppugunduri, Koustav Sarkar, Oishi Mukherjee, Kaviya Manoharan, Iyshwarya B. K, Melvin George (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13294383.txt.
Description
Chakradhara Rao S. Uppugunduri leads a 2026 pilot study on blood microRNAs for heart attack diagnosis in South India. Attacks strike earlier and harder in South Asian groups, and local marker data were thin. A prospective group held 45 heart attack patients, 71 stable coronary disease patients, and 100 healthy controls, with 20 chosen microRNAs measured within a day of symptoms for cases.
Nine markers shifted clearly in attack cases, and clustering split attack profiles cleanly while stable disease sat midway. One marker hit a perfect discrimination area of 1.000 in the reported analysis. Linked pathways covered matrix contact, platelet firing, and PI3K signaling. Larger cohorts must confirm the striking pilot scores.
Catalog record
| CREATOR | Chakradhara Rao S. Uppugunduri, Koustav Sarkar, Oishi Mukherjee, Kaviya Manoharan, Iyshwarya B. K, Melvin George |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39776 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |