Comparative genomic analysis of RNA-binding proteins across some drug resistant and sensitive Staphylococcus aureus
Magda M Awad, Yehia A Osman, Mohamed Abdelmoteleb · 2026
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Description
Magda M Awad, Yehia A Osman, and Mohamed Abdelmoteleb compare RNA-binding proteins across staph genomes in a 2026 bioinformatics study. Staphylococcus aureus adapts well to hosts, and proteins that grip RNA steer gene activity after copying, yet bacterial roles stay murky. Genomes and proteomes of 51 pathogenic strains were sorted into drug-resistant and drug-sensitive groups and family trees were built from single-letter variants.
Eight conserved RNA-binding proteins emerged. Cold shock proteins A and B plus S1 domain proteins differed in family pattern, binding parts, and simulated motion between resistant and sensitive strains. Such splits hint that RNA control helps drive toughness and could offer drug targets.
Catalog record
| CREATOR | Magda M Awad, Yehia A Osman, Mohamed Abdelmoteleb |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44251 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |