Applicability of methylliberine as a salivary marker under postprandial conditions
Toni Wildgrube, Nikolaus Alexander Link, Benno Ritucci, Michael Grimm, Stefan Engeli, Werner Weitschies, Philipp Schick · 2026
Read Applicability of methylliberine as a salivary marker under postprandial conditions by Toni Wildgrube, Nikolaus Alexander Link, Benno Ritucci, Michael Grimm, Stefan Engeli, Werner Weitschies, Philipp Schick (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13293696.txt.
Description
Toni Wildgrube and colleagues test, in a 2026 study, whether methylliberine, a caffeine-like compound, can serve as a saliva marker for stomach emptying after meals. Saliva tests spare blood draws, and caffeine is the standard marker because food barely changes its behavior.
Twelve healthy volunteers took coated tablets with both compounds while fasting and after light and heavy meals in a crossover design. Both appeared fast in saliva, and meals delayed peak times for both, matching slower emptying. Caffeine exposure held steady across meals, while methylliberine exposure fell as meal calories rose, clearly after the fatty meal. Its fed-state use is thus limited.
Catalog record
| CREATOR | Toni Wildgrube, Nikolaus Alexander Link, Benno Ritucci, Michael Grimm, Stefan Engeli, Werner Weitschies, Philipp Schick |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46778 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |