Tenosynovial and Transverse Carpal Ligament Biopsy for Early Transthyretin Amyloidosis Cardiomyopathy Detection: A Systematic Review and African American Retrospective Cohort Study
Shireen Dogar, Punn Punnakanta, Marcus D Williams, Youssef al Hamda, Somjade Songcharoen, Mark A Dodson, Marc E Walker · 2026
Read Tenosynovial and Transverse Carpal Ligament Biopsy for Early Transthyretin Amyloidosis Cardiomyopathy Detection: A Systematic Review and African American Retrospective Cohort Study by Shireen Dogar, Punn Punnakanta, Marcus D Williams, Youssef al Hamda, Somjade Songcharoen, Mark A Dodson, Marc E Walker (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13293664.txt.
Description
Shireen Dogar and colleagues combine, in a 2026 paper, a literature review and hospital cohort on wrist tissue biopsy as an early test for heart amyloidosis. A wrist operation for carpal tunnel release offers a chance to spot the protein buildup before heart failure starts.
The review of 22 studies from 2017 to 2025 found amyloid in 10% to 30% of wrist specimens, a range the authors report. At their center, 89 patients had biopsy during release surgery from 2021 to 2025, over half of them African American. No specimen showed amyloid on staining. Better patient picking and sampling rules are needed, the authors conclude.
Catalog record
| CREATOR | Shireen Dogar, Punn Punnakanta, Marcus D Williams, Youssef al Hamda, Somjade Songcharoen, Mark A Dodson, Marc E Walker |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 14470 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |