Efficacy of calcium hypophosphite toothpaste in remineralizing initial caries in vitro
Bennett Tochukwu Amaechi, Kelly Yang, Amos Chinedu Obiefuna, Temitope Olabisi Omosebi, Pascal Fandrich, Erik Schulze zur Wiesche, Joachim Enax · 2026
Read Efficacy of calcium hypophosphite toothpaste in remineralizing initial caries in vitro by Bennett Tochukwu Amaechi, Kelly Yang, Amos Chinedu Obiefuna, Temitope Olabisi Omosebi, Pascal Fandrich, Erik Schulze zur Wiesche, Joachim Enax (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13292511.txt.
Description
Bennett Tochukwu Amaechi and colleagues run a 2026 bench test on whether adding calcium hypophosphite supercharges hydroxyapatite toothpaste against early tooth decay. One hundred twenty bovine tooth blocks were split among four pastes: hydroxyapatite alone, hydroxyapatite plus 1 percent calcium compound, the calcium compound alone, and standard 1450 ppm fluoride. A microbial model first grew early lesions, then two weeks of pH cycling with daily paste treatments tested repair.
Every paste remineralized significantly. The combination won clearly, reaching 95.7 percent remineralization against 67.3 for fluoride, 69.4 for hydroxyapatite alone, and 80.4 for the calcium paste in the reported means. The authors credit the additive's ready calcium ions. They say the pairing could strengthen fluoride-free remineralizing pastes, pending mouth-based trials.
Catalog record
| CREATOR | Bennett Tochukwu Amaechi, Kelly Yang, Amos Chinedu Obiefuna, Temitope Olabisi Omosebi, Pascal Fandrich, Erik Schulze zur Wiesche, Joachim Enax |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40633 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |