Curcumin-mediated photodynamic inactivation of Vibrio parahaemolyticus biofilms on stainless steel: Oxidative damage and degradation of exopolysaccharides

Xiulian Huang, Lu Chen, Shiying Tang, Zhiyun Peng, Zihao Lin, Konglong Feng, Langhong Wang, Yong Zhao, Qiaohui Zeng, Jing Jing Wang · 2026

Read Curcumin-mediated photodynamic inactivation of Vibrio parahaemolyticus biofilms on stainless steel: Oxidative damage and degradation of exopolysaccharides by Xiulian Huang, Lu Chen, Shiying Tang, Zhiyun Peng, Zihao Lin, Konglong Feng, Langhong Wang, Yong Zhao, Qiaohui Zeng, Jing Jing Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13292477.txt.

Description

Xiulian Huang's team tests a 2026 light-activated attack on Vibrio parahaemolyticus biofilms fouling stainless steel in food plants. The treatment pairs curcumin with blue light, a photodynamic method that generates reactive oxygen inside the biofilm. The team aimed squarely at exopolysaccharides, the glue sugars holding the biofilm's protective matrix together.

At 60 micromolar curcumin under 9.17 joules per square centimeter of blue light, the treatment erased over 60 percent of biofilm mass and killed 5.0 log units of cells per milliliter in their tests. Chemistry showed the light-driven reaction snipped sugar linkages and shrank the glue molecules, collapsing their hydrogen-bond networks. The matrix turned less water-shy, less sticky, and less cohesive, so the biofilm broke apart. The authors offer the mechanism as design guidance for stronger photodynamic sanitation.

Catalog record

CREATORXiulian Huang, Lu Chen, Shiying Tang, Zhiyun Peng, Zihao Lin, Konglong Feng, Langhong Wang, Yong Zhao, Qiaohui Zeng, Jing Jing Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48139
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13292477

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