Non‐pharmacological interventions for anxiety and depression in Parkinson's disease

Tengfei Li, Jiyuan Shi, Qingyong Zheng, Jian-Guo Xu, Mingyue Zhang, Yalin Ren, BoWa Zhang, Zheng Li · 2026

Read Non‐pharmacological interventions for anxiety and depression in Parkinson's disease by Tengfei Li, Jiyuan Shi, Qingyong Zheng, Jian-Guo Xu, Mingyue Zhang, Yalin Ren, BoWa Zhang, Zheng Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13292111.txt.

Description

Tengfei Li and co-authors set out a 2026 Cochrane protocol for comparing drug-free treatments for anxiety and depression in Parkinson's disease. Mood problems affect roughly 40 to 50 percent of people with Parkinson's and deepen dependence, decline, and mortality risk. The protocol states the review's aim plainly: judge how well non-drug options work and how safe they are.

Because it is a protocol, no results are reported yet. The background explains how Parkinson's disrupts dopamine, serotonin, and noradrenaline circuits feeding the limbic system and amygdala-driven fear pathways. It also notes that women and younger-onset patients often carry heavier mood symptoms. The finished review is meant to guide care for a symptom group that drugs alone handle imperfectly.

Catalog record

CREATORTengfei Li, Jiyuan Shi, Qingyong Zheng, Jian-Guo Xu, Mingyue Zhang, Yalin Ren, BoWa Zhang, Zheng Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52611
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13292111

Browse the full library · About the Tower of Babel