In-vivo Antioxidant Effects of Emodin on Ischemia-Reperfusion Injury of Rat’s Skeletal Muscle
Dilara Yiğit, Gürsel Levent Oktar, Hüseyin Demirtaş, Abdullah Özer, Ayşegül Küçük, Zeynep Yığman, Esra Tekin, Mustafa Arslan · 2026
Read In-vivo Antioxidant Effects of Emodin on Ischemia-Reperfusion Injury of Rat’s Skeletal Muscle by Dilara Yiğit, Gürsel Levent Oktar, Hüseyin Demirtaş, Abdullah Özer, Ayşegül Küçük, Zeynep Yığman, Esra Tekin, Mustafa Arslan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13291782.txt.
Description
Dilara Yiğit and colleagues report a 2026 animal experiment testing whether emodin, a plant-derived anthraquinone, protects rat leg muscle from ischemia-reperfusion injury. Twenty-four male Wistar rats were split into four groups: sham, emodin alone, injury alone, and injury plus emodin. Injury was produced by clamping the lower aorta for 45 minutes, then restoring flow for 120 minutes.
Injured muscle showed higher malondialdehyde and lower catalase activity, signs of oxidative damage. Emodin at 20 mg/kg lowered the malondialdehyde levels and partly restored catalase, though superoxide dismutase and glutathione did not change. Tissue damage such as fiber disarray, swelling, and neutrophil buildup also eased, without vanishing. The authors call the protection partial and urge work on the pathways involved.
Catalog record
| CREATOR | Dilara Yiğit, Gürsel Levent Oktar, Hüseyin Demirtaş, Abdullah Özer, Ayşegül Küçük, Zeynep Yığman, Esra Tekin, Mustafa Arslan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34464 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |