Genome-wide analysis of mRNA regionalization in a giant single cell

Ashley R. Albright, Connie Yan, David Angeles-Albores, Yina Hudnall, Tatyana Makushok, Jamarc Allen-Henderson, Wallace F. Marshall · 2026

Read Genome-wide analysis of mRNA regionalization in a giant single cell by Ashley R. Albright, Connie Yan, David Angeles-Albores, Yina Hudnall, Tatyana Makushok, Jamarc Allen-Henderson, Wallace F. Marshall (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13291615.txt.

Description

One giant cell can pattern itself like a tiny embryo. Ashley R. Albright leads a 2026 study of the single-celled Stentor. This striped cell is a millimeter long. Cut pieces can regrow whole forms without spilling.

Surgery plus gene tools mapped RNA by cell region. Messages from distinct genes piled up in distinct zones. Head and tail regions held different RNA sets. The cell thus sorts its own instructions in space. Similar tricks pattern animal embryos across many cells. Size lets each cell fragment yield enough material to test. Single cells may be smarter architects than assumed.

Catalog record

CREATORAshley R. Albright, Connie Yan, David Angeles-Albores, Yina Hudnall, Tatyana Makushok, Jamarc Allen-Henderson, Wallace F. Marshall
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51678
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13291615

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