Appendectomy and colorectal cancer: a mini review from the perspective of gut microbiota and mucosal immunity
Shuai Wang, Jingbo Lv, Li Wang, Xueyuan Cao · 2026
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Description
Shuai Wang and colleagues review the appendix and colon cancer risk in a 2026 short article. The appendix was once seen as useless. New work casts it as a home for gut microbes and immune tissue. That shift raises a fresh question about removing it.
Past studies gave mixed answers on cancer after appendix removal. Some found higher risk soon after surgery. Newer work blames early detection bias for much of that signal. Lab studies still show plausible paths through microbes and inflammation. Effects may also differ by tumor site. The authors call for care in reading old data. No simple claim that removal raises long-term risk holds up.
Catalog record
| CREATOR | Shuai Wang, Jingbo Lv, Li Wang, Xueyuan Cao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27278 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |