Research progress and antibacterial mechanisms of plant essential oils as alternative therapies for periodontitis

Yan Huang, Xiaoyi Liu, Li Chen, Maolin Li, Ying Xia, Kun Yang · 2026

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Description

Plant essential oils attack gum-disease bacteria on several fronts at once, Yan Huang and colleagues summarize in a 2026 review of alternatives for periodontitis care. With standard drugs facing resistance, the review gathers what is known about oils' antibacterial strength and how they work.

Many oils suppressed key plaque pathogens, including Porphyromonas gingivalis, often at minimum inhibitory concentrations below 100 μg/mL, and some blocked biofilm formation at even lower doses. Their weapons include tearing bacterial membranes, jamming metabolism, switching off virulence genes, and interrupting quorum sensing. Single components such as carvacrol, thymol, and eugenol carry much of the punch, and carriers like nanoemulsions and liposomes can steady the oils and deliver them better. The authors flag poor water solubility, leftover toxicity, and instability as the work that remains.

Catalog record

CREATORYan Huang, Xiaoyi Liu, Li Chen, Maolin Li, Ying Xia, Kun Yang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE81125
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13290721

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