Mediator subunit MED25 represses ABI5-dependent activation of erucic acid biosynthetic gene FAE1 in Brassica napus
Zhuang Li, Shouchuan Zhi, Yongkang Tang, Huan Li, Mengliang Tian, Xiaobin Pu, Yongcheng Wu · 2026
Read Mediator subunit MED25 represses ABI5-dependent activation of erucic acid biosynthetic gene FAE1 in Brassica napus by Zhuang Li, Shouchuan Zhi, Yongkang Tang, Huan Li, Mengliang Tian, Xiaobin Pu, Yongcheng Wu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13290517.txt.
Description
A seed-oil regulator gains a partner in oilseed rape, Zhuang Li and colleagues show in a 2026 study of erucic acid production in Brassica napus. The transcription factor ABI5, known for holding back germination, also switches on the marker gene FAE1 and raises erucic acid levels in seeds.
The team showed that the two genes' activity overlaps in developing seeds and that ABI5 sits in the nucleus and can drive gene expression. The mediator subunit MED25 binds ABI5 in living cells and in test-tube assays, and reporter and DNA-binding experiments place it inside the circuit that controls FAE1. Plants overexpressing ABI5 made more FAE1 transcript and more erucic acid. Li and colleagues present the pair as a mechanism steering long-chain fatty acid build-up, of interest for oil quality and industrial uses.
Catalog record
| CREATOR | Zhuang Li, Shouchuan Zhi, Yongkang Tang, Huan Li, Mengliang Tian, Xiaobin Pu, Yongcheng Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64387 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |