Multimodal treatment and long-term survival in a rare case of melanoma with pancreatic and splenic metastases: a case report and literature review
Yanhua Mou, Lan Han, Jing Yu, Hui Shen, Hui Li, Lichao Xu, Qingfeng Li · 2026
Read Multimodal treatment and long-term survival in a rare case of melanoma with pancreatic and splenic metastases: a case report and literature review by Yanhua Mou, Lan Han, Jing Yu, Hui Shen, Hui Li, Lichao Xu, Qingfeng Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13290512.txt.
Description
A man whose melanoma spread to his pancreas and spleen, two rare destinations, survives long-term in a 2026 case report and literature review by Yanhua Mou and colleagues. The 55-year-old had a lower-leg melanoma removed, only for widespread metastases to appear within five months.
He cycled through several regimens, including immunotherapy with toripalimab, combinations with anlotinib, and temozolomide, before surgeons removed the pancreatic and spleen lesions. Testing of that tissue found a BRAF V600 mutation, which opened the door to targeted drugs, dabrafenib plus trametinib. At last follow-up on March 6, 2025, he remained stable. Mou and colleagues stress molecular re-testing, persistence with treatment, and team-based care for such complex cases.
Catalog record
| CREATOR | Yanhua Mou, Lan Han, Jing Yu, Hui Shen, Hui Li, Lichao Xu, Qingfeng Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23578 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |