The oral-respiratory interface: modulation of Streptococcus pneumoniae serotype adhesion by the periodontal pathogen Porphyromonas gingivalis W83

Chrysanti Murad, Yasmin Hanifa Salma, Imam Megantara, Achadiyani Achadiyani, Ani Melani Maskoen · 2026

Read The oral-respiratory interface: modulation of Streptococcus pneumoniae serotype adhesion by the periodontal pathogen Porphyromonas gingivalis W83 by Chrysanti Murad, Yasmin Hanifa Salma, Imam Megantara, Achadiyani Achadiyani, Ani Melani Maskoen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13290081.txt.

Description

Chrysanti Murad and coauthors test a 2026 lab question on whether a gum disease germ helps lung pneumococcal germs stick to airway cells by serotype. Porphyromonas gingivalis can raise a host receptor that pneumococci exploit, called PAFR. Lung lining cells were primed for 24 hours with fluid from the W83 strain, then exposed to four pneumococcal serotypes for adhesion counts.

Priming raised receptor gene activity clearly in the cell model. Adhesion jumped significantly for serotypes 4 and 7F after priming in the counts. Thick-coated serotypes 3 and 6A rose only slightly without statistical firmness overall. The mouth-lung partnership thus favors select pneumococcal types, shaping pneumonia risk by strain.

Catalog record

CREATORChrysanti Murad, Yasmin Hanifa Salma, Imam Megantara, Achadiyani Achadiyani, Ani Melani Maskoen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24598
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13290081

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