Regulatory T Cells Along the Pancreatitis–Pancreatic Cancer Continuum: Context-Dependent Immune Control and Therapeutic Opportunities
Hongmei Li, Pingping Wang, Hongsuo Chen, Chi Wang, Abdullah Al-Danakh, Zhenyu Jiang · 2026
Read Regulatory T Cells Along the Pancreatitis–Pancreatic Cancer Continuum: Context-Dependent Immune Control and Therapeutic Opportunities by Hongmei Li, Pingping Wang, Hongsuo Chen, Chi Wang, Abdullah Al-Danakh, Zhenyu Jiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13289651.txt.
Description
Hongmei Li and colleagues review a 2026 topic on regulatory T cells along the path from pancreas inflammation to pancreatic cancer. These cells keep immunity in check and limit tissue harm, but in pancreatic cancer they can shield tumors from attack. Acute inflammation, chronic inflammation, and cancer share immune features that shift cell roles over time and place.
In early inflammation the cells protect by calming excess attack, while in tumors they may block useful defense. Simply wiping them out can even speed tumor growth in some settings, the review warns. Differences in cell subtypes, tissue residence, and disease stage decide the net effect. The authors map drug ideas that tune rather than erase these cells.
Catalog record
| CREATOR | Hongmei Li, Pingping Wang, Hongsuo Chen, Chi Wang, Abdullah Al-Danakh, Zhenyu Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54343 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |