Stage-resolved mapping of RP105 (CD180)-negative B cells reveals residual plasmablast-lineage skewing in SLE: a cross-sectional study
Ayana Kanagawa, Akihito Maruyama, Tatsuki Shibuta, Mitsuteru Akahoshi, Sachiko Soejima, Yoshifumi Tada, Syuichi Koarada · 2026
Read Stage-resolved mapping of RP105 (CD180)-negative B cells reveals residual plasmablast-lineage skewing in SLE: a cross-sectional study by Ayana Kanagawa, Akihito Maruyama, Tatsuki Shibuta, Mitsuteru Akahoshi, Sachiko Soejima, Yoshifumi Tada, Syuichi Koarada (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13289216.txt.
Description
Ayana Kanagawa and colleagues map B cells in lupus in 2026. Their study sorts cells by loss of a marker called CD180. Quiet disease may not mean a normal immune state. Blood cells came from three groups. Healthy controls numbered 27 adults.
Active lupus held 29 patients. Quiet lupus held just 14 patients. All quiet cases had five-plus years of calm. Six stages were set along the marker-loss path. Active disease pushed cells toward antibody-making stages. Quiet disease kept a smaller such push. It still topped healthy levels. One travel marker fell early in both lupus groups. The authors call for long-term follow-up studies.
Catalog record
| CREATOR | Ayana Kanagawa, Akihito Maruyama, Tatsuki Shibuta, Mitsuteru Akahoshi, Sachiko Soejima, Yoshifumi Tada, Syuichi Koarada |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37751 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |