Right Ventricular Mechanical Dyssynchrony Reflects Hemodynamic Load in Pre‐Capillary Pulmonary Hypertension

Sachiyo Igata, Nobuhiro Tahara, Atsuko Tahara, Akihiro Honda, Tadahiro Kugai, Yoshiko Eto, Shoko Maeda‐Ogata, Yoshihiro Fukumoto · 2026

Read Right Ventricular Mechanical Dyssynchrony Reflects Hemodynamic Load in Pre‐Capillary Pulmonary Hypertension by Sachiyo Igata, Nobuhiro Tahara, Atsuko Tahara, Akihiro Honda, Tadahiro Kugai, Yoshiko Eto, Shoko Maeda‐Ogata, Yoshihiro Fukumoto (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13288177.txt.

Description

Sachiyo Igata and co-authors measured timing spread in the right heart chamber in 2026 in 30 patients with high pressure in the lung arteries from narrowed vessels. Scans, ultrasound speckle tracking, and direct pressure readings through a catheter were combined in one visit.

Wider timing spread tracked with higher artery pressure and higher flow resistance, and with weaker matching between chamber and artery. After adjustment, artery pressure alone predicted the spread, covering about a quarter of its variation. Chamber size and pumping share did not. Dyssynchrony appeared even when chamber function was only mildly reduced. The authors propose the ultrasound measure as a stand-in for invasive pressure checks.

Catalog record

CREATORSachiyo Igata, Nobuhiro Tahara, Atsuko Tahara, Akihiro Honda, Tadahiro Kugai, Yoshiko Eto, Shoko Maeda‐Ogata, Yoshihiro Fukumoto
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43458
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13288177

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