Different injection speeds produce distinct temporal dynamics of optic nerve sheath diameter increase during caudal block in children: a prospective randomized trial
Wenshuang Yang, Ding Han, Siyuan Xie, Shiya Zou, Ya Ma, Guimin Huang, Shoudong Pan · 2026
Read Different injection speeds produce distinct temporal dynamics of optic nerve sheath diameter increase during caudal block in children: a prospective randomized trial by Wenshuang Yang, Ding Han, Siyuan Xie, Shiya Zou, Ya Ma, Guimin Huang, Shoudong Pan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13286833.txt.
Description
Wenshuang Yang and colleagues ask whether the speed of injecting anesthetic during a caudal block changes pressure effects inside children's heads. The 2026 randomized trial enrolled eighty children aged one to three having perineal surgery. Caudal blocks, given near the tailbone, are routine in children, yet injected fluid briefly widens the optic nerve sheath, a sign of raised pressure.
Ultrasound measured the sheath before and after injection at two speeds. Fast injection peaked early, while slow injection rose gradually and peaked later. Peak size was the same, and no child was harmed. Vital signs stayed alike between groups. Because the slower rise is gentler, the authors recommend slow injection for routine practice.
Catalog record
| CREATOR | Wenshuang Yang, Ding Han, Siyuan Xie, Shiya Zou, Ya Ma, Guimin Huang, Shoudong Pan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |