Mini-Review: Allicin as a Potential Neuroprotective Compound in Neurological Disorders

Wen-Rui Tang, Ke Qian Chen · 2026

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Description

Wen-Rui Tang and Ke Qian Chen offer a 2026 mini-review of allicin, the sharp compound in garlic, as a brain-protecting agent. Brain disorders from Alzheimer's disease to stroke share drivers such as cell stress, swelling, and cell death. The review gathers work on how allicin is made, measured, and delivered, and what it has done in lab models of those disorders.

Across animal studies, allicin curbed oxidative stress and inflammation, guarded cell power plants, and kept the blood-brain barrier tighter. Gains appeared in models of memory loss, Parkinson's disease, head injury, and several forms of stroke and bleeding. Two flaws hold the field back: the compound breaks down fast and reaches the body poorly in raw form. The authors press for proper human trials and new carriers that keep allicin stable and on target.

Catalog record

CREATORWen-Rui Tang, Ke Qian Chen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29165
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13285917

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