Vitamin E alleviates energy stress-induced injury in yak granulosa cells by blocking the AMPK/mTOR-mitophagy-ferroptosis axis
Hecheng Zhang, Guorong YE, Linjiao Bai, Peiyan Du, Mengjiao Wang, Furong Feng, Hongliang Li, Xueli Ma, Jiamei Lu, Jiangfeng Fan · 2026
Read Vitamin E alleviates energy stress-induced injury in yak granulosa cells by blocking the AMPK/mTOR-mitophagy-ferroptosis axis by Hecheng Zhang, Guorong YE, Linjiao Bai, Peiyan Du, Mengjiao Wang, Furong Feng, Hongliang Li, Xueli Ma, Jiamei Lu, Jiangfeng Fan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13285493.txt.
Description
Hecheng Zhang and co-authors traced how vitamin E shields yak egg-support cells from energy stress, in a 2026 study. Stress in these granulosa cells is a leading cause of poor female fertility, and vitamin E protects them by means that were unclear. The team stressed the cells in culture and followed the signaling chain that followed.
Energy stress switched on a sensor pathway that triggered self-eating of mitochondria, then a form of iron-driven cell death, and finally programmed death. Vitamin E cut in along that chain: it eased the deaths, restored two channel proteins that keep cells talking, and normalized the death markers. The work names a full route for the vitamin's protection.
Catalog record
| CREATOR | Hecheng Zhang, Guorong YE, Linjiao Bai, Peiyan Du, Mengjiao Wang, Furong Feng, Hongliang Li, Xueli Ma, Jiamei Lu, Jiangfeng Fan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |